The first issue of Philosophical Transactions of the Royal Society was published on 6 March 1665, meaning the journal is celebrating its 350th birthday today.
The gallery above features some highlights from its illustrious publishing history, including a gruesome account of an early blood transfusion in 1666, Isaac Newton at his brilliant best, and an image from the first atomic explosion.
Scroll through for some of the many landmark papers from the world’s first scientific journal.