These are all the papers relating to the "biology and medicine" research fronts in the article What are the hot research areas that might spark the next big bang?, published in Times Higher Education on 25 May 2017.
Research front: Structure, transmission, action, and potential inhibitors of Zika virus
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Paper 1 |
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Title: Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells |
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Author(s): Nowakowski, TJ (Nowakowski, Tomasz J.); Pollen, AA (Pollen, Alex A.); Di Lullo, E (Di Lullo, Elizabeth); Sandoval-Espinosa, C (Sandoval-Espinosa, Carmen); Bershteyn, M (Bershteyn, Marina); Kriegstein, AR (Kriegstein, Arnold R.) |
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Source: CELL STEM CELL Volume: 18 Issue: 5 Pages: 591-596 DOI: 10.1016/j.stem.2016.03.012 Published: MAY 5 2016 |
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Times Cited in Web of Science Core Collection: 43 |
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Total Times Cited: 44 |
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Paper 2 |
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Title: The 3.8 angstrom resolution cryo-EM structure of Zika virus |
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Author(s): Sirohi, D (Sirohi, Devika); Chen, ZG (Chen, Zhenguo); Sun, L (Sun, Lei); Klose, T (Klose, Thomas); Pierson, TC (Pierson, Theodore C.); Rossmann, MG (Rossmann, Michael G.); Kuhn, RJ (Kuhn, Richard J.) |
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Source: SCIENCE Volume: 352 Issue: 6284 Pages: 467-470 DOI: 10.1126/science.aaf5316 Published: APR 22 2016 |
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Times Cited in Web of Science Core Collection: 42 |
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Total Times Cited: 46 |
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Paper 3 |
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Title: Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection |
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Author(s): Bayer, A (Bayer, Avraham); Lennemann, NJ (Lennemann, Nicholas J.); Ouyang, YS (Ouyang, Yingshi); Bramley, JC (Bramley, John C.); Morosky, S (Morosky, Stefanie); Marques, ETD (De Azeved Marques, Ernesto Torres, Jr.); Cherry, S (Cherry, Sara); Sadovsky, Y (Sadovsky, Yoel); Coyne, CB (Coyne, Carolyn B.) |
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Source: CELL HOST & MICROBE Volume: 19 Issue: 5 Pages: 705-712 DOI: 10.1016/j.chom.2016.03.008 Published: MAY 11 2016 |
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Times Cited in Web of Science Core Collection: 39 |
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Total Times Cited: 39 |
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Paper 4 |
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Title: Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3 |
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Author(s): Dang, J (Dang, Jason); Tiwari, SK (Tiwari, Shashi Kant); Lichinchi, G (Lichinchi, Gianluigi); Qin, Y (Qin, Yue); Patil, VS (Patil, Veena S.); Eroshkin, AM (Eroshkin, Alexey M.); Rana, TM (Rana, Tariq M.) |
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Source: CELL STEM CELL Volume: 19 Issue: 2 Pages: 258-265 DOI: 10.1016/j.stem.2016.04.014 Published: AUG 4 2016 |
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Times Cited in Web of Science Core Collection: 34 |
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Total Times Cited: 34 |
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Paper 5 |
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Title: Structure of the thermally stable Zika virus |
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Author(s): Kostyuchenko, VA (Kostyuchenko, Victor A.); Lim, EXY (Lim, Elisa X. Y.); Zhang, SJ (Zhang, Shuijun); Fibriansah, G (Fibriansah, Guntur); Ng, TS (Ng, Thiam-Seng); Ooi, JSG (Ooi, Justin S. G.); Shi, J (Shi, Jian); Lok, SM (Lok, Shee-Mei) |
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Source: NATURE Volume: 533 Issue: 7603 Pages: 425-+ DOI: 10.1038/nature17994 Published: MAY 19 2016 |
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Times Cited in Web of Science Core Collection: 34 |
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Total Times Cited: 35 |
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Paper 6 |
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Title: Vertical transmission of Zika virus targeting the radial glial cells affects cortex development of offspring mice |
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Author(s): Wu, KY (Wu, Kong-Yan); Zuo, GL (Zuo, Guo-Long); Li, XF (Li, Xiao-Feng); Ye, Q (Ye, Qing); Deng, YQ (Deng, Yong-Qiang); Huang, XY (Huang, Xing-Yao); Cao, WC (Cao, Wu-Chun); Qin, CF (Qin, Cheng-Feng); Luo, ZG (Luo, Zhen-Ge) |
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Source: CELL RESEARCH Volume: 26 Issue: 6 Pages: 645-654 DOI: 10.1038/cr.2016.58 Published: JUN 2016 |
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Times Cited in Web of Science Core Collection: 33 |
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Total Times Cited: 33 |
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Paper 7 |
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Title: Characterization of Lethal Zika Virus Infection in AG129 Mice |
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Author(s): Aliota, MT (Aliota, Matthew T.); Caine, EA (Caine, Elizabeth A.); Walker, EC (Walker, Emma C.); Larkin, KE (Larkin, Katrina E.); Camacho, E (Camacho, Erwin); Osorio, JE (Osorio, Jorge E.) |
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Source: PLOS NEGLECTED TROPICAL DISEASES Volume: 10 Issue: 4 Article Number: e0004682 DOI: 10.1371/journal.pntd.0004682 Published: APR 2016 |
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Times Cited in Web of Science Core Collection: 30 |
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Total Times Cited: 30 |
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Paper 8 |
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Title: A Susceptible Mouse Model for Zika Virus Infection |
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Author(s): Dowall, SD (Dowall, Stuart D.); Graham, VA (Graham, Victoria A.); Rayner, E (Rayner, Emma); Atkinson, B (Atkinson, Barry); Hall, G (Hall, Graham); Watson, RJ (Watson, Robert J.); Bosworth, A (Bosworth, Andrew); Bonney, LC (Bonney, Laura C.); Kitchen, S (Kitchen, Samantha); Hewson, R (Hewson, Roger) |
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Source: PLOS NEGLECTED TROPICAL DISEASES Volume: 10 Issue: 5 Article Number: e0004658 DOI: 10.1371/journal.pntd.0004658 Published: MAY 2016 |
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Times Cited in Web of Science Core Collection: 25 |
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Total Times Cited: 25 |
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Paper 9 |
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Title: Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody |
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Author(s): Dai, LP (Dai, Lianpan); Song, J (Song, Jian); Lu, XS (Lu, Xishan); Deng, YQ (Deng, Yong-Qiang); Musyoki, AM (Musyoki, Abednego Moki); Cheng, HJ (Cheng, Huijun); Zhang, YF (Zhang, Yanfang); Yuan, Y (Yuan, Yuan); Song, H (Song, Hao); Haywood, J (Haywood, Joel); Xiao, HX (Xiao, Haixia); Yan, JH (Yan, Jinghua); Shi, Y (Shi, Yi); Qin, CF (Qin, Cheng-Feng); Qi, JX (Qi, Jianxun); Gao, GF (Gao, George F.) |
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Source: CELL HOST & MICROBE Volume: 19 Issue: 5 Pages: 696-704 DOI: 10.1016/j.chom.2016.04.013 Published: MAY 11 2016 |
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Times Cited in Web of Science Core Collection: 23 |
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Total Times Cited: 25 |
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Paper 10 |
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Title: Zika Virus Infects Human Placental Macrophages |
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Author(s): Quicke, KM (Quicke, Kendra M.); Bowen, JR (Bowen, James R.); Johnson, EL (Johnson, Erica L.); McDonald, CE (McDonald, Circe E.); Ma, HL (Ma, Huailiang); O'Neal, JT (O'Neal, Justin T.); Rajakumar, A (Rajakumar, Augustine); Wrammert, J (Wrammert, Jens); Rimawi, BH (Rimawi, Bassam H.); Pulendran, B (Pulendran, Bali); Schinazi, RF (Schinazi, Raymond F.); Chakraborty, R (Chakraborty, Rana); Suthar, MS (Suthar, Mehul S.) |
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Source: CELL HOST & MICROBE Volume: 20 Issue: 1 Pages: 83-90 DOI: 10.1016/j.chom.2016.05.015 Published: JUL 13 2016 |
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Times Cited in Web of Science Core Collection: 20 |
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Total Times Cited: 20 |
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Paper 11 |
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Title: Structural basis of potent Zika-dengue virus antibody cross-neutralization |
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Author(s): Barba-Spaeth, G (Barba-Spaeth, Giovanna); Dejnirattisai, W (Dejnirattisai, Wanwisa); Rouvinski, A (Rouvinski, Alexander); Vaney, MC (Vaney, Marie-Christine); Medits, I (Medits, Iris); Sharma, A (Sharma, Arvind); Simon-Loriere, E (Simon-Loriere, Etienne); Sakuntabhai, A (Sakuntabhai, Anavaj); Cao-Lormeau, VM (Cao-Lormeau, Van-Mai); Haouz, A (Haouz, Ahmed); England, P (England, Patrick); Stiasny, K (Stiasny, Karin); Mongkolsapaya, J (Mongkolsapaya, Juthathip); Heinz, FX (Heinz, Franz X.); Screaton, GR (Screaton, Gavin R.); Rey, FA (Rey, Felix A.) |
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Source: NATURE Volume: 536 Issue: 7614 Pages: 48-+ DOI: 10.1038/nature18938 Published: AUG 4 2016 |
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Times Cited in Web of Science Core Collection: 19 |
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Total Times Cited: 19 |
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Paper 12 |
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Title: Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling |
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Author(s): Grant, A (Grant, Alesha); Ponia, SS (Ponia, Sanket S.); Tripathi, S (Tripathi, Shashank); Balasubramaniam, V (Balasubramaniam, Vinod); Miorin, L (Miorin, Lisa); Sourisseau, M (Sourisseau, Marion); Schwarz, MC (Schwarz, Megan C.); Sanchez-Seco, MP (Paz Sanchez-Seco, Mari); Evans, MJ (Evans, Matthew J.); Best, SM (Best, Sonja M.); Garcia-Sastre, A (Garcia-Sastre, Adolfo) |
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Source: CELL HOST & MICROBE Volume: 19 Issue: 6 Pages: 882-890 DOI: 10.1016/j.chom.2016.05.009 Published: JUN 8 2016 |
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Times Cited in Web of Science Core Collection: 18 |
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Total Times Cited: 18 |
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Paper 13 |
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Title: Zika virus damages the human placental barrier and presents marked fetal neurotropism |
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Author(s): de Noronha, L (de Noronha, Lucia); Zanluca, C (Zanluca, Camila); Azevedo, MLV (Viola Azevedo, Marina Luize); Luz, KG (Luz, Kleber Giovanni); dos Santos, CND (Duarte dos Santos, Claudia Nunes) |
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Source: MEMORIAS DO INSTITUTO OSWALDO CRUZ Volume: 111 Issue: 5 Pages: 287-+ DOI: 10.1590/0074-02760160085 Published: MAY 2016 |
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Times Cited in Web of Science Core Collection: 17 |
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Total Times Cited: 18 |
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Paper 14 |
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Title: Vaccine protection against Zika virus from Brazil |
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Author(s): Larocca, RA (Larocca, Rafael A.); Abbink, P (Abbink, Peter); Peron, JPS (Peron, Jean Pierre S.); Zanotto, PMD (Zanotto, Paolo M. de A.); Iampietro, MJ (Iampietro, M. Justin); Badamchi-Zadeh, A (Badamchi-Zadeh, Alexander); Boyd, M (Boyd, Michael); Ng'ang'a, D (Ng'ang'a, David); Kirilova, M (Kirilova, Marinela); Nityanandam, R (Nityanandam, Ramya); Mercado, NB (Mercado, Noe B.); Li, ZF (Li, Zhenfeng); Moseley, ET (Moseley, Edward T.); Bricault, CA (Bricault, Christine A.); Borducchi, EN (Borducchi, Erica N.); Giglio, PB (Giglio, Patricia B.); Jetton, D (Jetton, David); Neubauer, G (Neubauer, George); Nkolola, JP (Nkolola, Joseph P.); Maxfield, LF (Maxfield, Lori F.); De La Barrera, RA (De La Barrera, Rafael A.); Jarman, RG (Jarman, Richard G.); Eckels, KH (Eckels, Kenneth H.); Michael, NL (Michael, Nelson L.); Thomas, SJ (Thomas, Stephen J.); Barouch, DH (Barouch, Dan H.) |
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Source: NATURE Volume: 536 Issue: 7617 Pages: 474-+ DOI: 10.1038/nature18952 Published: AUG 25 2016 |
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Times Cited in Web of Science Core Collection: 16 |
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Total Times Cited: 17 |
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Paper 15 |
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Title: A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection |
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Author(s): Barrows, NJ (Barrows, Nicholas J.); Campos, RK (Campos, Rafael K.); Powell, ST (Powell, Steven T.); Prasanth, KR (Prasanth, K. Reddisiva); Schott-Lerner, G (Schott-Lerner, Geraldine); Soto-Acosta, R (Soto-Acosta, Ruben); Galarza-Munoz, G (Galarza-Munoz, Gaddiel); McGrath, EL (McGrath, Erica L.); Urrabaz-Garza, R (Urrabaz-Garza, Rheanna); Gao, JL (Gao, Junling); Wu, P (Wu, Ping); Menon, R (Menon, Ramkumar); Saade, G (Saade, George); Fernandez-Salas, I (Fernandez-Salas, Ildefonso); Rossi, SL (Rossi, Shannan L.); Vasilakis, N (Vasilakis, Nikos); Routh, A (Routh, Andrew); Bradrick, SS (Bradrick, Shelton S.); Garcia-Blanco, MA (Garcia-Blanco, Mariano A.) |
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Source: CELL HOST & MICROBE Volume: 20 Issue: 2 Pages: 259-270 DOI: 10.1016/j.chom.2016.07.004 Published: AUG 10 2016 |
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Times Cited in Web of Science Core Collection: 16 |
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Total Times Cited: 16 |
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Paper 16 |
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Title: Zika virus NS1 structure reveals diversity of electrostatic surfaces among flaviviruses |
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Author(s): Song, H (Song, Hao); Qi, JX (Qi, Jianxun); Haywood, J (Haywood, Joel); Shi, Y (Shi, Yi); Gao, GF (Gao, George F.) |
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Source: NATURE STRUCTURAL & MOLECULAR BIOLOGY Volume: 23 Issue: 5 Pages: 456-458 DOI: 10.1038/nsmb.3213 Published: MAY 2016 |
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Times Cited in Web of Science Core Collection: 15 |
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Total Times Cited: 16 |
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Paper 17 |
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Title: Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission |
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Author(s): Tabata, T (Tabata, Takako); Petitt, M (Petitt, Matthew); Puerta-Guardo, H (Puerta-Guardo, Henry); Michlmayr, D (Michlmayr, Daniela); Wang, C (Wang, Chunling); Fang-Hoover, J (Fang-Hoover, June); Harris, E (Harris, Eva); Pereira, L (Pereira, Lenore) |
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Source: CELL HOST & MICROBE Volume: 20 Issue: 2 Pages: 155-166 DOI: 10.1016/j.chom.2016.07.002 Published: AUG 10 2016 |
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Times Cited in Web of Science Core Collection: 13 |
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Total Times Cited: 13 |
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Paper 18 |
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Title: Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus |
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Author(s): Priyamvada, L (Priyamvada, Lalita); Quicke, KM (Quicke, Kendra M.); Hudson, WH (Hudson, William H.); Onlamoon, N (Onlamoon, Nattawat); Sewatanon, J (Sewatanon, Jaturong); Edupuganti, S (Edupuganti, Srilatha); Pattanapanyasat, K (Pattanapanyasat, Kovit); Chokephaibulkit, K (Chokephaibulkit, Kulkanya); Mulligan, MJ (Mulligan, Mark J.); Wilson, PC (Wilson, Patrick C.); Ahmed, R (Ahmed, Rafi); Suthar, MS (Suthar, Mehul S.); Wrammert, J (Wrammert, Jens) |
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Source: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 113 Issue: 28 Pages: 7852-7857 DOI: 10.1073/pnas.1607931113 Published: JUL 12 2016 |
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Times Cited in Web of Science Core Collection: 13 |
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Total Times Cited: 13 |
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Paper 19 |
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Title: The Viral Polymerase Inhibitor 7-Deaza-2 '-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model |
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Author(s): Zmurko, J (Zmurko, Joanna); Marques, RE (Marques, Rafael E.); Schols, D (Schols, Dominique); Verbeken, E (Verbeken, Erik); Kaptein, SJF (Kaptein, Suzanne J. F.); Neyts, J (Neyts, Johan) |
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Source: PLOS NEGLECTED TROPICAL DISEASES Volume: 10 Issue: 5 Article Number: e0004695 DOI: 10.1371/journal.pntd.0004695 Published: MAY 2016 |
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Times Cited in Web of Science Core Collection: 13 |
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Total Times Cited: 13 |
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Paper 20 |
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Title: Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys |
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Author(s): Abbink, P (Abbink, Peter); Larocca, RA (Larocca, Rafael A.); De La Barrera, RA (De La Barrera, Rafael A.); Bricault, CA (Bricault, Christine A.); Moseley, ET (Moseley, Edward T.); Boyd, M (Boyd, Michael); Kirilova, M (Kirilova, Marinela); Li, ZF (Li, Zhenfeng); Ng'ang'a, D (Ng'ang'a, David); Nanayakkara, O (Nanayakkara, Ovini); Nityanandam, R (Nityanandam, Ramya); Mercado, NB (Mercado, Noe B.); Borducchi, EN (Borducchi, Erica N.); Agarwal, A (Agarwal, Arshi); Brinkman, AL (Brinkman, Amanda L.); Cabral, C (Cabral, Crystal); Chandrashekar, A (Chandrashekar, Abishek); Giglio, PB (Giglio, Patricia B.); Jetton, D (Jetton, David); Jimenez, J (Jimenez, Jessica); Lee, BC (Lee, Benjamin C.); Mojta, S (Mojta, Shanell); Molloy, K (Molloy, Katherine); Shetty, M (Shetty, Mayuri); Neubauer, GH (Neubauer, George H.); Stephenson, KE (Stephenson, Kathryn E.); Peron, JPS (Peron, Jean Pierre S.); Zanotto, PMD (Zanotto, Paolo M. de A.); Misamore, J (Misamore, Johnathan); Finneyfrock, B (Finneyfrock, Brad); Lewis, MG (Lewis, Mark G.); Alter, G (Alter, Galit); Modjarrad, K (Modjarrad, Kayvon); Jarman, RG (Jarman, Richard G.); Eckels, KH (Eckels, Kenneth H.); Michael, NL (Michael, Nelson L.); Thomas, SJ (Thomas, Stephen J.); Barouch, DH (Barouch, Dan H.) |
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Source: SCIENCE Volume: 353 Issue: 6304 Pages: 1129-1132 DOI: 10.1126/science.aah6157 Published: SEP 9 2016 |
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Times Cited in Web of Science Core Collection: 12 |
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Total Times Cited: 12 |
Research front: Identification of bromodomain inhibitors
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Paper 1 |
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Title: Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains |
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Author(s): Hay, DA (Hay, Duncan A.); Fedorov, O (Fedorov, Oleg); Martin, S (Martin, Sarah); Singleton, DC (Singleton, Dean C.); Tallant, C (Tallant, Cynthia); Wells, C (Wells, Christopher); Picaud, S (Picaud, Sarah); Philpott, M (Philpott, Martin); Monteiro, OP (Monteiro, Octovia P.); Rogers, CM (Rogers, Catherine M.); Conway, SJ (Conway, Stuart J.); Rooney, TPC (Rooney, Timothy P. C.); Tumber, A (Tumber, Anthony); Yapp, C (Yapp, Clarence); Filippakopoulos, P (Filippakopoulos, Panagis); Bunnage, ME (Bunnage, Mark E.); Muller, S (Mueller, Susanne); Knapp, S (Knapp, Stefan); Schofield, CJ (Schofield, Christopher J.); Brennan, PE (Brennan, Paul E.) |
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Source: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 136 Issue: 26 Pages: 9308-9319 DOI: 10.1021/ja412434f Published: JUL 2 2014 |
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Times Cited in Web of Science Core Collection: 69 |
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Total Times Cited: 69 |
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Paper 2 |
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Title: Small Molecule Inhibitors of Bromodomain-Acetyl-lysine Interactions |
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Author(s): Brand, M (Brand, Michael); Measures, AM (Measures, Angelina M.); Wilson, BG (Wilson, Brian G.); Cortopassi, WA (Cortopassi, Wilian A.); Alexander, R (Alexander, Rikki); Hoss, M (Hoess, Matthias); Hewings, DS (Hewings, David S.); Rooney, TPC (Rooney, Timothy P. C.); Paton, RS (Paton, Robert S.); Conway, SJ (Conway, Stuart J.) |
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Source: ACS CHEMICAL BIOLOGY Volume: 10 Issue: 1 Pages: 22-39 DOI: 10.1021/cb500996u Published: JAN 2015 |
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Times Cited in Web of Science Core Collection: 42 |
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Total Times Cited: 42 |
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Paper 3 |
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Title: LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor |
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Author(s): Clark, PGK (Clark, Peter G. K.); Vieira, LCC (Vieira, Lucas C. C.); Tallant, C (Tallant, Cynthia); Fedorov, O (Fedorov, Oleg); Singleton, DC (Singleton, Dean C.); Rogers, CM (Rogers, Catherine M.); Monteiro, OP (Monteiro, Octovia P.); Bennett, JM (Bennett, James M.); Baronio, R (Baronio, Roberta); Muller, S (Mueller, Susanne); Daniels, DL (Daniels, Danette L.); Mendez, J (Mendez, Jacqui); Knapp, S (Knapp, Stefan); Brennan, PE (Brennan, Paul E.); Dixon, DJ (Dixon, Darren J.) |
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Source: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Volume: 54 Issue: 21 Pages: 6217-6221 DOI: 10.1002/anie.201501394 Published: MAY 18 2015 |
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Times Cited in Web of Science Core Collection: 37 |
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Total Times Cited: 38 |
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Paper 4 |
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Title: Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition |
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Author(s): Theodoulou, NH (Theodoulou, Natalie H.); Bamborough, P (Bamborough, Paul); Bannister, AJ (Bannister, Andrew J.); Becher, I (Becher, Isabelle); Bit, RA (Bit, Rino A.); Che, KH (Che, Ka Hing); Chung, CW (Chung, Chun-wa); Dittmann, A (Dittmann, Antje); Drewes, G (Drewes, Gerard); Drewry, DH (Drewry, David H.); Gordon, L (Gordon, Laurie); Grandi, P (Grandi, Paola); Leveridge, M (Leveridge, Melanie); Lindon, M (Lindon, Matthew); Michon, AM (Michon, Anne-Marie); Molnar, J (Molnar, Judit); Robson, SC (Robson, Samuel C.); Tomkinson, NCO (Tomkinson, Nicholas C. O.); Kouzarides, T (Kouzarides, Tony); Prinjha, RK (Prinjha, Rab K.); Humphreys, PG (Humphreys, Philip G.) |
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Source: JOURNAL OF MEDICINAL CHEMISTRY Volume: 59 Issue: 4 Special Issue: SI Pages: 1425-1439 DOI: 10.1021/acs.jmedchem.5b00256 Published: FEB 25 2016 |
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Times Cited in Web of Science Core Collection: 26 |
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Total Times Cited: 26 |
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Paper 5 |
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Title: Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B |
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Author(s): Chen, PL (Chen, Peiling); Chaikuad, A (Chaikuad, Apirat); Bamborough, P (Bamborough, Paul); Bantscheff, M (Bantscheff, Marcus); Bountra, C (Bountra, Chas); Chung, CW (Chung, Chun-wa); Fedorov, O (Fedorov, Oleg); Grandi, P (Grandi, Paola); Jung, D (Jung, David); Lesniak, R (Lesniak, Robert); Lindon, M (Lindon, Matthew); Muller, S (Mueller, Susanne); Philpott, M (Philpott, Martin); Prinjha, R (Prinjha, Rab); Rogers, C (Rogers, Catherine); Selenski, C (Selenski, Carolyn); Tallant, C (Tallant, Cynthia); Werner, T (Werner, Thilo); Willson, TM (Willson, Timothy M.); Knapp, S (Knapp, Stefan); Drewry, DH (Drewry, David H.) |
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Source: JOURNAL OF MEDICINAL CHEMISTRY Volume: 59 Issue: 4 Special Issue: SI Pages: 1410-1424 DOI: 10.1021/acs.jmedchem.5b00209 Published: FEB 25 2016 |
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Times Cited in Web of Science Core Collection: 25 |
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Total Times Cited: 25 |
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Paper 6 |
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Title: The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNFMutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies |
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Author(s): Vangamudi, B (Vangamudi, Bhavatarini); Paul, TA (Paul, Thomas A.); Shah, PK (Shah, Parantu K.); Kost-Alimova, M (Kost-Alimova, Maria); Nottebaum, L (Nottebaum, Lisa); Shi, X (Shi, Xi); Zhan, YA (Zhan, Yanai); Leo, E (Leo, Elisabetta); Mahadeshwar, HS (Mahadeshwar, Harshad S.); Protopopov, A (Protopopov, Alexei); Futreal, A (Futreal, Andrew); Tieu, TN (Tieu, Trang N.); Peoples, M (Peoples, Mike); Heffernan, TP (Heffernan, Timothy P.); Marszalek, JR (Marszalek, Joseph R.); Toniatti, C (Toniatti, Carlo); Petrocchi, A (Petrocchi, Alessia); Verhelle, D (Verhelle, Dominique); Owen, DR (Owen, Dafydd R.); Draetta, G (Draetta, Giulio); Jones, P (Jones, Philip); Palmer, WS (Palmer, Wylie S.); Sharma, S (Sharma, Shikhar); Andersen, JN (Andersen, Jannik N.) |
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Source: CANCER RESEARCH Volume: 75 Issue: 18 Pages: 3865-3878 DOI: 10.1158/0008-5472.CAN-14-3798 Published: SEP 15 2015 |
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Times Cited in Web of Science Core Collection: 23 |
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Total Times Cited: 23 |
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Paper 7 |
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Title: Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF |
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Author(s): Bennett, J (Bennett, James); Fedorov, O (Fedorov, Oleg); Tallant, C (Tallant, Cynthia); Monteiro, O (Monteiro, Octovia); Meier, J (Meier, Julia); Gamble, V (Gamble, Vicky); Savitsky, P (Savitsky, Pavel); Nunez-Alonso, GA (Nunez-Alonso, Graciela A.); Haendler, B (Haendler, Bernard); Rogers, C (Rogers, Catherine); Brennan, PE (Brennan, Paul E.); Muller, S (Mueller, Susanne); Knapp, S (Knapp, Stefan) |
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Source: JOURNAL OF MEDICINAL CHEMISTRY Volume: 59 Issue: 4 Special Issue: SI Pages: 1642-1647 DOI: 10.1021/acs.jmedchem.5b00458 Published: FEB 25 2016 |
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Times Cited in Web of Science Core Collection: 22 |
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Total Times Cited: 22 |
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Paper 8 |
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Title: Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors |
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Author(s): Romero, FA (Romero, F. Anthony); Taylor, AM (Taylor, Alexander M.); Crawford, TD (Crawford, Terry D.); Tsui, V (Tsui, Vickie); Cote, A (Cote, Alexandre); Magnuson, S (Magnuson, Steven) |
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Source: JOURNAL OF MEDICINAL CHEMISTRY Volume: 59 Issue: 4 Special Issue: SI Pages: 1271-1298 DOI: 10.1021/acs.jmedchem.5b01514 Published: FEB 25 2016 |
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Times Cited in Web of Science Core Collection: 21 |
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Total Times Cited: 21 |
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Paper 9 |
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Title: Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor |
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Author(s): Palmer, WS (Palmer, Wylie S.); Poncet-Montange, G (Poncet-Montange, Guillaume); Liu, G (Liu, Gang); Petrocchi, A (Petrocchi, Alessia); Reyna, N (Reyna, Naphtali); Subramanian, G (Subramanian, Govindan); Theroff, J (Theroff, Jay); Yau, A (Yau, Anne); Kost-Alimova, M (Kost-Alimova, Maria); Bardenhagen, JP (Bardenhagen, Jennifer P.); Leo, E (Leo, Elisabetta); Shepard, HE (Shepard, Hannah E.); Tieu, TN (Tieu, Trang N.); Shi, X (Shi, Xi); Zhao, YN (Zhao, Yanai); Zhao, SP (Zhao, Shuping); Barton, MC (Barton, Michelle C.); Draetta, G (Draetta, Giulio); Toniatti, C (Toniatti, Carlo); Jones, P (Jones, Philip); Do, MG (Do, Mary Geck); Andersen, JN (Andersen, Jannik N.) |
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Source: JOURNAL OF MEDICINAL CHEMISTRY Volume: 59 Issue: 4 Special Issue: SI Pages: 1440-1454 DOI: 10.1021/acs.jmedchem.5b00405 Published: FEB 25 2016 |
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Times Cited in Web of Science Core Collection: 17 |
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Total Times Cited: 18 |
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Paper 10 |
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Title: Fragment-Based Design of Selective Nanomolar Ligands of the CREBBP Bromodomain |
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Author(s): Unzue, A (Unzue, Andrea); Xu, M (Xu, Min); Dong, J (Dong, Jing); Wiedmer, L (Wiedmer, Lars); Spiliotopoulos, D (Spiliotopoulos, Dimitrios); Caflisch, A (Caflisch, Amedeo); Nevado, C (Nevado, Cristina) |
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Source: JOURNAL OF MEDICINAL CHEMISTRY Volume: 59 Issue: 4 Special Issue: SI Pages: 1350-1356 DOI: 10.1021/acs.jmedchem.5b00172 Published: FEB 25 2016 |
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Times Cited in Web of Science Core Collection: 13 |
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Total Times Cited: 13 |
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Paper 11 |
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Title: Discovery of CREBBP Bromodomain Inhibitors by High-Throughput Docking and Hit Optimization Guided by Molecular Dynamics |
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Author(s): Xu, M (Xu, Min); Unzue, A (Unzue, Andrea); Dong, J (Dong, Jing); Spiliotopoulos, D (Spiliotopoulos, Dimitrios); Nevado, C (Nevado, Cristina); Caflisch, A (Caflisch, Amedeo) |
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Source: JOURNAL OF MEDICINAL CHEMISTRY Volume: 59 Issue: 4 Special Issue: SI Pages: 1340-1349 DOI: 10.1021/acs.jmedchem.5b00171 Published: FEB 25 2016 |
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Times Cited in Web of Science Core Collection: 13 |
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Total Times Cited: 13 |
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Paper 12 |
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Title: Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor |
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Author(s): Martin, LJ (Martin, Laetitia J.); Koegl, M (Koegl, Manfred); Bader, G (Bader, Gerd); Cockcroft, XL (Cockcroft, Xiao-Ling); Fedorov, O (Fedorov, Oleg); Fiegen, D (Fiegen, Dennis); Gerstberger, T (Gerstberger, Thomas); Hofmann, MH (Hofmann, Marco H.); Hohmann, AF (Hohmann, Anja F.); Kessler, D (Kessler, Dirk); Knapp, S (Knapp, Stefan); Knesl, P (Knesl, Petr); Kornigg, S (Kornigg, Stefan); Muller, S (Muller, Susanne); Nar, H (Nar, Herbert); Rogers, C (Rogers, Catherine); Rumpel, K (Rumpel, Klaus); Schaaf, O (Schaaf, Otmar); Steurer, S (Steurer, Steffen); Tallan, C (Tallan, Cynthia); Vakoc, CR (Vakoc, Christopher R.); Zeeb, M (Zeeb, Markus); Zoephel, A (Zoephel, Andreas); Pearson, M (Pearson, Mark); Boehmelt, G (Boehmelt, Guido); McConnell, D (McConnell, Darryl) |
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Source: JOURNAL OF MEDICINAL CHEMISTRY Volume: 59 Issue: 10 Pages: 4462-4475 DOI: 10.1021/acs.jmedchem.5b01865 Published: MAY 26 2016 |
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Times Cited in Web of Science Core Collection: 11 |
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Total Times Cited: 11 |
Research front: Tumor-associated neutrophils and T cell response
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Paper 1 |
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Title: Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer |
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Author(s): Eruslanov, EB (Eruslanov, Evgeniy B.); Bhojnagarwala, PS (Bhojnagarwala, Pratik S.); Quatromoni, JG (Quatromoni, Jon G.); Stephen, TL (Stephen, Tom Li); Ranganathan, A (Ranganathan, Anjana); Deshpande, C (Deshpande, Charuhas); Akimova, T (Akimova, Tatiana); Vachani, A (Vachani, Anil); Litzky, L (Litzky, Leslie); Hancock, WW (Hancock, Wayne W.); Conejo-Garcia, JR (Conejo-Garcia, Jose R.); Feldman, M (Feldman, Michael); Albeida, SM (Albeida, Steven M.); Singhal, S (Singhal, Sunil) |
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Source: JOURNAL OF CLINICAL INVESTIGATION Volume: 124 Issue: 12 Pages: 5466-5480 DOI: 10.1172/JCI7053 Published: DEC 2014 |
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Times Cited in Web of Science Core Collection: 63 |
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Total Times Cited: 64 |
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Paper 2 |
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Title: Neutrophils support lung colonization of metastasis-initiating breast cancer cells |
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Author(s): Wculek, SK (Wculek, Stefanie K.); Malanchi, I (Malanchi, Ilaria) |
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Source: NATURE Volume: 528 Issue: 7582 Pages: 413-+ DOI: 10.1038/nature16140 Published: DEC 17 2015 |
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Times Cited in Web of Science Core Collection: 48 |
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Total Times Cited: 50 |
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Paper 3 |
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Title: Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils |
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Author(s): Casbon, AJ (Casbon, Amy-Jo); Reynaud, D (Reynaud, Damien); Park, C (Park, Chanhyuk); Khuc, E (Khuc, Emily); Gan, DD (Gan, Dennis D.); Schepers, K (Schepers, Koen); Passegue, E (Passegue, Emmanuelle); Werb, Z (Werb, Zena) |
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Source: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 112 Issue: 6 Pages: E566-E575 DOI: 10.1073/pnas.1424927112 Published: FEB 10 2015 |
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Times Cited in Web of Science Core Collection: 36 |
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Total Times Cited: 36 |
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Paper 4 |
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Title: MET is required for the recruitment of anti-tumoural neutrophils |
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Author(s): Finisguerra, V (Finisguerra, Veronica); Di Conza, G (Di Conza, Giusy); Di Matteo, M (Di Matteo, Mario); Serneels, J (Serneels, Jens); Costa, S (Costa, Sandra); Thompson, AAR (Thompson, A. A. Roger); Wauters, E (Wauters, Els); Walmsley, S (Walmsley, Sarah); Prenen, H (Prenen, Hans); Granot, Z (Granot, Zvi); Casazza, A (Casazza, Andrea); Mazzone, M (Mazzone, Massimiliano) |
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Source: NATURE Volume: 522 Issue: 7556 Pages: 349-+ DOI: 10.1038/nature14407 Published: JUN 18 2015 |
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Times Cited in Web of Science Core Collection: 34 |
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Total Times Cited: 34 |
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Paper 5 |
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Title: Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study |
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Author(s): Mandruzzato, S (Mandruzzato, Susanna); Brandau, S (Brandau, Sven); Britten, CM (Britten, Cedrik M.); Bronte, V (Bronte, Vincenzo); Damuzzo, V (Damuzzo, Vera); Gouttefangeas, C (Gouttefangeas, Cecile); Maurer, D (Maurer, Dominik); Ottensmeier, C (Ottensmeier, Christian); van der Burg, SH (van der Burg, Sjoerd H.); Welters, MJP (Welters, Marij J. P.); Walter, S (Walter, Steffen) |
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Source: CANCER IMMUNOLOGY IMMUNOTHERAPY Volume: 65 Issue: 2 Pages: 161-169 DOI: 10.1007/s00262-015-1782-5 Published: FEB 2016 |
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Times Cited in Web of Science Core Collection: 16 |
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Total Times Cited: 16 |
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Paper 6 |
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Title: Neutrophils in the Tumor Microenvironment |
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Author(s): Powell, DR (Powell, Davalyn R.); Huttenlocher, A (Huttenlocher, Anna) |
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Source: TRENDS IN IMMUNOLOGY Volume: 37 Issue: 1 Pages: 41-52 DOI: 10.1016/j.it.2015.11.008 Published: JAN 2016 |
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Times Cited in Web of Science Core Collection: 14 |
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Total Times Cited: 14 |
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Paper 7 |
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Title: Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human |
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Author(s): Andzinski, L (Andzinski, Lisa); Kasnitz, N (Kasnitz, Nadine); Stahnke, S (Stahnke, Stephanie); Wu, CF (Wu, Ching-Fang); Gereke, M (Gereke, Marcus); von Kockritz-Blickwede, M (von Koeckritz-Blickwede, Maren); Schilling, B (Schilling, Bastian); Brandau, S (Brandau, Sven); Weiss, S (Weiss, Siegfried); Jablonska, J (Jablonska, Jadwiga) |
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Source: INTERNATIONAL JOURNAL OF CANCER Volume: 138 Issue: 8 Pages: 1982-1993 DOI: 10.1002/ijc.29945 Published: APR 15 2016 |
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Times Cited in Web of Science Core Collection: 13 |
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Total Times Cited: 14 |
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Paper 8 |
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Title: The Complex Role of Neutrophils in Tumor Angiogenesis and Metastasis |
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Author(s): Liang, W (Liang, Wei); Ferrara, N (Ferrara, Napoleone) |
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Source: CANCER IMMUNOLOGY RESEARCH Volume: 4 Issue: 2 Pages: 83-91 DOI: 10.1158/2326-6066.CIR-15-0313 Published: FEB 2016 |
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Times Cited in Web of Science Core Collection: 13 |
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Total Times Cited: 14 |
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Paper 9 |
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Title: Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells |
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Author(s): Spiegel, A (Spiegel, Asaf); Brooks, MW (Brooks, Mary W.); Houshyar, S (Houshyar, Samin); Reinhardt, F (Reinhardt, Ferenc); Ardolino, M (Ardolino, Michele); Fessler, E (Fessler, Evelyn); Chen, MB (Chen, Michelle B.); Krall, JA (Krall, Jordan A.); DeCock, J (DeCock, Jasmine); Zervantonakis, IK (Zervantonakis, Ioannis K.); Iannello, A (Iannello, Alexandre); Iwamoto, Y (Iwamoto, Yoshiko); Cortez-Retamozo, V (Cortez-Retamozo, Virna); Kamm, RD (Kamm, Roger D.); Pittet, MJ (Pittet, Mikael J.); Raulet, DH (Raulet, David H.); Weinberg, RA (Weinberg, Robert A.) |
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Source: CANCER DISCOVERY Volume: 6 Issue: 6 Pages: 630-649 DOI: 10.1158/2159-8290.CD-15-1157 Published: JUN 2016 |
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Times Cited in Web of Science Core Collection: 10 |
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Total Times Cited: 10 |
Research front: Transmission and persistence of Ebola virus
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Paper 1 |
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Title: Persistence of Ebola Virus in Ocular Fluid during Convalescence |
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Author(s): Varkey, JB (Varkey, Jay B.); Shantha, JG (Shantha, Jessica G.); Crozier, I (Crozier, Ian); Kraft, CS (Kraft, Colleen S.); Lyon, GM (Lyon, G. Marshall); Mehta, AK (Mehta, Aneesh K.); Kumar, G (Kumar, Gokul); Smith, JR (Smith, Justine R.); Kainulainen, MH (Kainulainen, Markus H.); Whitmer, S (Whitmer, Shannon); Stroher, U (Stroeher, Ute); Uyeki, TM (Uyeki, Timothy M.); Ribner, BS (Ribner, Bruce S.); Yeh, S (Yeh, Steven) |
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Source: NEW ENGLAND JOURNAL OF MEDICINE Volume: 372 Issue: 25 Pages: 2423-2427 DOI: 10.1056/NEJMoa1500306 Published: JUN 18 2015 |
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Times Cited in Web of Science Core Collection: 94 |
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Total Times Cited: 94 |
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Paper 2 |
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Title: Molecular Evidence of Sexual Transmission of Ebola Virus |
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Author(s): Mate, SE (Mate, S. E.); Kugelman, JR (Kugelman, J. R.); Nyenswah, TG (Nyenswah, T. G.); Ladner, JT (Ladner, J. T.); Wiley, MR (Wiley, M. R.); Cordier-Lassalle, T (Cordier-Lassalle, T.); Christie, A (Christie, A.); Schroth, GP (Schroth, G. P.); Gross, SM (Gross, S. M.); Davies-Wayne, GJ (Davies-Wayne, G. J.); Shinde, SA (Shinde, S. A.); Murugan, R (Murugan, R.); Sieh, SB (Sieh, S. B.); Badio, M (Badio, M.); Fakoli, L (Fakoli, L.); Taweh, F (Taweh, F.); de Wit, E (de Wit, E.); van Doremalen, N (van Doremalen, N.); Munster, VJ (Munster, V. J.); Pettitt, J (Pettitt, J.); Prieto, K (Prieto, K.); Humrighouse, BW (Humrighouse, B. W.); Stroher, U (Stroeher, U.); DiClaro, JW (DiClaro, J. W.); Hensley, LE (Hensley, L. E.); Schoepp, RJ (Schoepp, R. J.); Safronetz, D (Safronetz, D.); Fair, J (Fair, J.); Kuhn, JH (Kuhn, J. H.); Blackley, DJ (Blackley, D. J.); Laney, AS (Laney, A. S.); Williams, DE (Williams, D. E.); Lo, T (Lo, T.); Gasasira, A (Gasasira, A.); Nichol, ST (Nichol, S. T.); Formenty, P (Formenty, P.); Kateh, FN (Kateh, F. N.); De Cock, KM (De Cock, K. M.); Bolay, F (Bolay, F.); Sanchez-Lockhart, M (Sanchez-Lockhart, M.); Palacios, G (Palacios, G.) |
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Source: NEW ENGLAND JOURNAL OF MEDICINE Volume: 373 Issue: 25 Pages: 2448-2454 DOI: 10.1056/NEJMoa1509773 Published: DEC 17 2015 |
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Times Cited in Web of Science Core Collection: 60 |
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Total Times Cited: 61 |
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Paper 3 |
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Title: Possible Sexual Transmission of Ebola Virus - Liberia, 2015 |
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Author(s): Christie, A (Christie, Athalia); Davies-Wayne, GJ (Davies-Wayne, Gloria J.); Cordier-Lasalle, T (Cordier-Lasalle, Thierry); Blackley, DJ (Blackley, David J.); Laney, AS (Laney, A. Scott); Williams, DE (Williams, Desmond E.); Shinde, SA (Shinde, Shivam A.); Badio, M (Badio, Moses); Lo, T (Lo, Terrence); Mate, SE (Mate, Suzanne E.); Ladner, JT (Ladner, Jason T.); Wiley, MR (Wiley, Michael R.); Kugelman, JR (Kugelman, Jeffrey R.); Palacios, G (Palacios, Gustavo); Holbrook, MR (Holbrook, Michael R.); Janosko, KB (Janosko, Krisztina B.); de Wit, E (de Wit, Emmie); van Doremalen, N (van Doremalen, Neeltje); Munster, VJ (Munster, Vincent J.); Pettitt, J (Pettitt, James); Schoepp, RJ (Schoepp, Randal J.); Verhenne, L (Verhenne, Leen); Evlampidou, I (Evlampidou, Iro); Kollie, KK (Kollie, Karsor K.); Sieh, SB (Sieh, Sonpon B.); Gasasira, A (Gasasira, Alex); Bolay, F (Bolay, Fatorma); Kateh, FN (Kateh, Francis N.); Nyenswah, TG (Nyenswah, Tolbert G.); De Cock, KM (De Cock, Kevin M.) |
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Source: MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT Volume: 64 Issue: 17 Pages: 479-481 Published: MAY 8 2015 |
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Times Cited in Web of Science Core Collection: 53 |
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Total Times Cited: 55 |
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Paper 4 |
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Title: Long-term sequelae after Ebola virus disease in Bundibugyo, Uganda: a retrospective cohort study |
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Author(s): Clark, DV (Clark, Danielle V.); Kibuuka, H (Kibuuka, Hannah); Millard, M (Millard, Monica); Wakabi, S (Wakabi, Salim); Lukwago, L (Lukwago, Luswa); Taylor, A (Taylor, Alison); Eller, MA (Eller, Michael A.); Eller, LA (Eller, Leigh Anne); Michael, NL (Michael, Nelson L.); Honko, AN (Honko, Anna N.); Olinger, GG (Olinger, Gene G., Jr.); Schoepp, RJ (Schoepp, Randal J.); Hepburn, MJ (Hepburn, Matthew J.); Hensley, LE (Hensley, Lisa E.); Robb, ML (Robb, Merlin L.) |
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Source: LANCET INFECTIOUS DISEASES Volume: 15 Issue: 8 Pages: 905-912 DOI: 10.1016/S1473-3099(15)70152-0 Published: AUG 2015 |
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Times Cited in Web of Science Core Collection: 42 |
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Total Times Cited: 42 |
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Paper 5 |
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Title: Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study |
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Author(s): Mattia, JG (Mattia, John G.); Vandy, MJ (Vandy, Mathew J.); Chang, JC (Chang, Joyce C.); Platt, DE (Platt, Devin E.); Dierberg, K (Dierberg, Kerry); Bausch, DG (Bausch, Daniel G.); Brooks, T (Brooks, Tim); Conteh, S (Conteh, Sampha); Crozier, I (Crozier, Ian); Fowler, RA (Fowler, Robert A.); Kamara, AP (Kamara, Amadu P.); Kang, C (Kang, Cindy); Mahadevan, S (Mahadevan, Srividya); Mansaray, Y (Mansaray, Yealie); Marcell, L (Marcell, Lauren); McKay, G (McKay, Gillian); O'Dempsey, T (O'Dempsey, Tim); Parris, V (Parris, Victoria); Pinto, R (Pinto, Ruxandra); Rangel, A (Rangel, Audrey); Salam, AP (Salam, Alex P.); Shantha, J (Shantha, Jessica); Wolfman, V (Wolfman, Vanessa); Yeh, S (Yeh, Steven); Chan, AK (Chan, Adrienne K.); Mishra, S (Mishra, Sharmistha) |
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Source: LANCET INFECTIOUS DISEASES Volume: 16 Issue: 3 Pages: 331-338 DOI: 10.1016/S1473-3099(15)00489-2 Published: MAR 2016 |
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Times Cited in Web of Science Core Collection: 20 |
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Total Times Cited: 20 |
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Paper 6 |
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Title: Systematic review of the literature on viral persistence and sexual transmission from recovered Ebola survivors: evidence and recommendations |
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Author(s): Thorson, A (Thorson, Anna); Formenty, P (Formenty, Pierre); Lofthouse, C (Lofthouse, Clare); Broutet, N (Broutet, Nathalie) |
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Source: BMJ OPEN Volume: 6 Issue: 1 Article Number: e008859 DOI: 10.1136/bmjopen-2015-008859 Published: 2016 |
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Times Cited in Web of Science Core Collection: 10 |
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Total Times Cited: 10 |