Hot papers in neuroscience

	Paper Author(s), journal	Citations
1	Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis T.%u2009J. Kwiatkowski, D.%u2009A. Bosco, A.%u2009L. Le Clerc et al Science, 323 (5918): 1205-1208, February 2009	72
1	Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse Patrick O. McGowan, Aya Sasaki, Ana C. D’Alessio et al Nature Neuroscience, 12 (3): 342-348, March 2009	72
1	How do you feel – now%3F The anterior insula and human awareness A.%u2009D. “Bud” Craig Nature Reviews Neuroscience, 10 (1): 59-70, January 2009	72
4	Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6 Caroline Vance, Boris Rogelj, Tibor Hortobagyi et al Science, 323 (5918): 1208-1211, February 2009	68
5	Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers Juha Lauren, David A. Gimbel, Haakon B. Nygaard et al Nature, 457 (7233): 1128-1132, 26 February 2009	66
6	Resting-State Functional Connectivity Reflects Structural Connectivity in the Default Mode Network Michael D. Greicius, Kaustubh Supekar, Vinod Menon et al Cerebral Cortex, 19 (1): 72-78, January 2009	54
7	Circular analysis in systems neuroscience: the dangers of double dipping Nikolaus Kriegeskorte, W. Kyle Simmons, Patrick S.%u2009F. Bellgowan et al Nature Neuroscience, 12 (5): 535-540, May 2009	43
8	Pathological and protective roles of glia in chronic pain Erin D. Milligan and Linda R. Watkins Nature Reviews Neuroscience, 10 (1): 23-36, January 2009	41
9	HDAC2 negatively regulates memory formation and synaptic plasticity Ji-Song Guan, Stephen J. Haggarty, Emanuela Giacometti et al Nature, 459 (7243): 55-60, 7 May 2009	31
10	Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke Marie Carlen, Konstantinos Meletis, Christian Goritz et al Nature Neuroscience, 12 (3): 259-267, March 2009	29

The data above were extracted from the Thomson Reuters Essential Science Indicators database. This database, currently covering the period January 1999 to December 2009, surveys only journal articles (original research reports and review articles) indexed by Thomson Reuters. Articles are assigned to a category based on the journals in which they were published and Thomson Reuters’ journal-to-category field-definition scheme. Individual articles published in multidisciplinary journals, such as Science or Nature, are assigned to their appropriate fields.

Hot papers are limited to those articles published in the past two years. A paper is selected if it meets a citation-frequency threshold determined for its field and bimonthly group. Citation-frequency distribu­tions are compiled for each field and cohort. Thresholds are set by finding the closest citation count that would select the top fraction of papers in each field and period. The fraction is set to retrieve about 0.1 per cent of papers.

Featured here are neuroscience papers published in 2009 that have already qualified as hot papers. All were published in the first half of that year, since citations require some time to accumulate.

For more information on Thomson Reuters Essential Science Indicators, see http://science.thomsonreuters. com/products/esi