Royal Society
Research Grants
- Award winner: Huiling Zhu
- Institution: University of Kent
- Value: £13,480
Development of energy-efficient radio resource allocation algorithms
Leverhulme Trust
Research Leadership Awards
Social sciences
- Award winner: Clare Bambra
- Institution: Durham University
- Value: £999,597
Local health inequalities in an age of austerity: the Stockton-on-Tees study
Research Project Grants
Sciences
- Award winner: Tomas Bellamy
- Institution: University of Nottingham
- Value: £2,242
Analysis of cell signalling networks using dynamic inputs
- Award winner: Shuang Zhang
- Institution: University of Birmingham
- Value: £242,820
Controlling Casimir force using optical metamaterials
Social sciences
- Award winner: David Deacon
- Institution: Loughborough University
- Value: £38,700
Changes in British election news reporting (1918-2010)
National Institute for Health Research
Health Technology Assessment Programme
- Award winner: Shakila Thangaratinam
- Institution: Queen Mary, University of London
- Value: £248,767
Effects of weight management interventions on maternal and fetal outcomes in pregnancy: individual patient data meta-analysis of randomised trials and model-based economic evaluation
The Wellcome Trust
Investigators in Medical Humanities
The value of these awards ranges from approximately £500,000 to just over £1 million for up to five years
- Award winner: Thomas Douglas
- Institution: University of Oxford
Neurointerventions in crime prevention: an ethical analysis
- Award winner: Sarah Franklin
- Institution: University of Cambridge
Fertilisation through a looking glass: a sociology of UK IVF in the late 20th century
In detail
Wellcome Trust Senior Investigator Award
Award winner: Sir Philip Cohen
Institution: University of Dundee
Value: £1.7 million
Elucidation of molecular mechanisms that activate the MyD88 signalling network
The project is aimed at understanding how the adaptor protein MyD88, one of the major cellular signalling networks of the innate immune system, operates. Nearly all toll-like receptors - crucial components of the immune system used for fighting bacteria, viruses and other pathogens - signal via MyD88. The team hopes to unravel the workings of the MyD88 network in molecular detail. This information will be critical in determining how the production of inflammatory mediators is regulated, why defects in this system lead to immunodeficiency, chronic inflammatory or autoimmune diseases, and to identify pathway components that are targets for therapeutic intervention. “I aim to identify all the major protein components of the MyD88 and how they are regulated,” Professor Cohen said. “In doing so, I hope to discover the best targets in the system for the development of improved drugs to treat chronic inflammatory and autoimmune diseases.”