National Institute for Health Research
Health Technology Assessment Programme
- Award winner: Nadine Foster
- Institution: Keele University
- Value: £1,179,586
Stratified care for patients with sciatica and suspended sciatica in primary care: a randomised trial (the SCOPiC trial - sciatica outcomes in primary care)
- Award winner: Miriam Wittmann
- Institution: University of Leeds
- Value: £2,148,481
Comparison of Alitretinoin with PUVA as the first-line treatment in patients with severe chronic hand eczema
Health Services and Delivery Research Programme
- Award winner: Alan Simpson
- Institution: City University London
- Value: £366,618
Cross-national comparative study of recovery-focused mental healthcare planning in acute inpatient mental health settings (COCAPP-A)
- Award winner: Sasha Shepperd
- Institution: University of Oxford
- Value: £2,303,703
A multi-centre randomised controlled trial of comprehensive geriatric assessment in an admission-avoidance hospital-at-home setting
Public Health Research Programme
- Award winner: Adam Fletcher
- Institution: Cardiff University
- Value: £339,604
The filter further education challenge pilot trial and process evaluation of a multi-level smoking prevention intervention in further education settings
Leverhulme Trust
International Network Grants
Sciences
- Award winner: Sasha Dall
- Institution: University of Exeter
- Value: £84,820
A Darwinian framework for phenotypically integrating genetic and epigenetic cues
Social sciences
- Award winner: Lindsay O’Dell
- Institution: The Open University
- Value: £38,201
Critical autism network: policy, practice and identities in five national contexts
- Award winner: David Valler
- Institution: Oxford Brookes University
- Value: £118,104
Global science ‘scapes: dimensions of transnationalism
- Award winner: Yingjie Yang
- Institution: De Montfort University
- Value: £124,997
Grey-systems and its applications
In detail
Dr Hadwen Trust
Award winner: John Connelly
Institution: Queen Mary University of London
Value: £117,823
High-throughput analysis of synthetic wound-healing microenvironment
This project will use human cells instead of animal cells to investigate wound healing and to improve the testing of drugs and therapeutics. Chronic, non-healing wounds are costly and difficult-to-treat conditions and are thus a major healthcare concern in the UK. The study aims to develop an engineered in vitro model of wound healing where many different components of the wound environment can be controlled and analysed. The team then intends to use this model to identify combinations of different adhesive proteins and internal-signalling molecules that regulate wound closure. The results of these studies will provide new and important insights into the regulatory mechanisms that are involved in wound healing. In addition, the study will establish a novel experimental platform that could replace many animal studies and improve pre-clinical testing of drugs and therapeutics.
