BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL
ERASysBio+ scheme
Sixteen transnational projects have received EUR24 million (£20 million) in funding under ERASysBio+, an initiative involving ministries and funding agencies from 13 countries that seeks to coordinate national research in systems biology and agree a common European research agenda. The projects below are part of 13 UK-based schemes that will receive EUR7.7 million from the BBSRC.
- Award winners: Andrew Cossins, University of Liverpool and Madan Babu, MRC Laboratory of Molecular Biology, Cambridge
- BBSRC funding: EUR660,000
- Total funding: EUR1.2 million
GRAPPLE - iterative modelling of gen-regulatory interactions underlying stress, disease and ageing in C. elegans
- Award winner: Peter Cook
- Institution: University of Oxford
- BBSRC funding: EUR460,000
- Total funding: EUR1.8 million
EpiGenSys - system biological determination of the epigenomic structure-function relation
- Award winners: David Whitmore, University College London and David Rand, Warwick Systems Biology Centre
- BBSRC funding: EUR690,000
- Total funding: EUR1.7 million
C5Sys - Circadian and cell cycle clock systems in cancer
- Award winner: Henning Walczak
- Institution: Imperial College London
- BBSRC funding: EUR600,000
- Total funding: EUR1.7 million
ApoNET - Systems analysis of death receptor signalling networks
- Award winner: Hans Westerhoff
- Institution: Manchester Interdisciplinary Biocentre
- BBSRC funding: EUR250,000
- Total funding: EUR2.5 million
livSYSiPS - the systems biology of network stress based on data generated from in vitro differentiated hepatocytes derived from individual-specific human iPS cells
NATIONAL INSTITUTE FOR HEALTH RESEARCH
Health Technology Assessment programme
- Award winner: Samuel McClinton
- Institution: Aberdeen Royal Infirmary
- Value: £1,452,458
Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: multicentre placebo controlled randomised trial of calcium channel blockers (nifedipine) and alpha blockers (tamsulosin)
- Award winner: Bashir Matata
- Institution: Liverpool NHS Trust
- Value: £169,833
The impact of continuous haemofiltration with high-volume fluid exchange during cardiopulmonary bypass surgery on the recovery of patients with impaired renal function - a pilot study
Efficacy and Mechanism Evaluation programme
- Award winner: Robin Spiller
- Institution: University of Nottingham
- Value: £724,082
Efficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D)
Public Health Research programme
- Award winner: Mark Petticrew
- Institution: London School of Hygiene and Tropical Medicine
- Value: £391,169
Crime, fear of crime and mental health: evidence synthesis of theory and effectiveness of interventions
IN DETAIL
- Award winner: Christopher Philip Bonell
- Institution: London School of Hygiene and Tropical Medicine
- Value: £182,641
The effects of schools and SE interventions on health: evidence-mapping and syntheses - in collaboration with the universities of Bristol and Cardiff, this study will seek to determine the effects that schools and specific "school-environment" (SE) interventions have on the health of young people and consider their cost, feasibility and acceptability.